Friday, March 4, 2011

Tight junctions compromised in atopic dermatitis

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Skin barrier compromise is a defining characteristic of atopic dermatitis (AD). Research has uncovered several possible explanations for th...
Tuesday, February 1, 2011

The scope and efficacy of intravenous immunoglobulin therapy

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Departing AAAAI president, Mark Ballow, MD, chose the mechanism(s) of action of IVIG (intravenous immunoglobulin) therapy as his contributio...
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Monday, January 31, 2011

The lung microbiome and asthma pathogenesis

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In this issue, Huang et al. ( J Allergy Clin Immunol 2011;127: 372-381.e3 ), reporting on behalf of the NHLBI’s Asthma Clinical Research Ne...
Friday, January 7, 2011

Gene-environment protective effects are context-dependent in development of asthma

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Recent genomic studies have begun to demonstrate that adaptive genotypes are only adaptive when expressed in their relevant context. In this...
Thursday, January 6, 2011

Advances in immunotherapy for allergies have increased safety and effectiveness

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Casale and Stokes take a look at new technologies and experimental therapies developed to improve on the standard approach of subcutaneous i...
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Monday, December 6, 2010

SARP reports differences in asthma genotypes & phenotypes are race-associated

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In this month’s issue, the Severe Asthma Research Program [SARP] presents their findings from a cross-sectional study of the SARP database, ...

Maternal antioxidant SNPs modify link between acetaminophen exposure in utero and childhood asthma

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Shaheen and colleagues report their findings from studies on acetaminophen and childhood asthma from the Avon Longitudinal Study of Parents ...