JACI Journal Club

Each month, the Editors of the Journal of Allergy and Clinical Immunology will select two JACI articles for discussion. Readers are invited to send in their questions and comments, which will be addressed by the authors. Articles highlighted on this blog are available free of charge from the links in each post.

Tuesday, November 5, 2013

Rhinovirus infection causes steroid resistance in airway epithelium through nuclear factor кB and c-Jun N-terminal kinase activation

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Inhaled glucocorticoids are often highly effective in treating symptoms of asthma exacerbations, however they are ineffective at treating a...
9 comments:

Predictors of response to tiotropium versus salmeterol in asthmatic adults

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The severity of asthma symptoms is well known to be attenuated by inhaled corticosteroid (ICS) due to their anti-inflammatory effect.  Long...
7 comments:
Monday, October 7, 2013

Exhaled NO levels and blood eosinophil counts independently associate with wheeze and asthma events

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Eosinophils and exhaled Nitric Oxide (NO) levels are prominent features of asthma.  It is known that both exhaled NO and blood eosinophil c...
2 comments:

A major allergen of public health relevance in the inner city of Baltimore

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The prevalence of asthma is ubiquitous across the United States, but the major allergens of public health relevance that contribute to the ...
6 comments:
Tuesday, September 3, 2013

Primary NK immunodeficiencies

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Keeping on the topic of natural killer cells, Jordan Orange, MD, PhD contributes a review on immunodeficiencies associated with NK cell dys...
1 comment:

Natural killer cell interactions in adaptive immunity

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This month, Deniz et al. give an overview of current knowledge about natural killer cells [NK cells] and their interface with pathways and ...
4 comments:
Wednesday, August 14, 2013

Is the human gut microbiota the critical mediator of health?

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In a review this month, Greer and co-authors present interesting information on just how much our health depends on the well-being and com...
1 comment:
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Journal of Allergy and Clinical Immunology
Founded in 1929, The Journal of Allergy and Clinical Immunology (JACI) is the official journal of the American Academy of Allergy, Asthma, and Immunology (AAAAI).
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