JACI Journal Club

Each month, the Editors of the Journal of Allergy and Clinical Immunology will select two JACI articles for discussion. Readers are invited to send in their questions and comments, which will be addressed by the authors. Articles highlighted on this blog are available free of charge from the links in each post.

Thursday, September 4, 2014

Allergens and the airway epithelium response: Gateway to allergic sensitization

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Allergic sensitization to inhaled antigens is increasingly common; however, the mechanisms remain poorly understood. Lung epithelial ce...
2 comments:

Epithelial barrier function: at the frontline of asthma immunology and allergic airway inflammation

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Airway epithelial cells are an important part of the innate immune system in the lung. Not only do they establish mucociliary clearance...
6 comments:
Tuesday, August 5, 2014

Risks for infection in patients with asthma (or other atopic conditions): is asthma more than a chronic airway disease?

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There is evidence that the presence of asthma can influence patients’ susceptibility to infections, yet research in this aspect of asthm...
3 comments:

Gene hunting in the genomic era: approaches to diagnostic dilemmas in primary immunodeficiencies

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Over the past four decades, over 180 molecular defects causing primary immunodeficiencies (PIDs) have been discovered through advances i...
2 comments:
Thursday, July 3, 2014

Progress in HIV-1 Vaccine Development

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Advances in HIV vaccine development have been hampered by roadblocks associated with failure to prevent infection. In recent years, a numbe...
16 comments:

Prenatal exposure to diesel exhaust induces asthma susceptibility through NK cell priming

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Asthma often begins early in life and is attributed to more than just genetic factors, because the prevalence continues to rise. Epidemiolo...
2 comments:
Monday, June 2, 2014

The effects of calcitriol treatment in glucocorticoid resistant asthma

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The current and most effective treatment for asthma therapy is the use of glucocorticoids by improving the clinical features and airway inf...
5 comments:
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Journal of Allergy and Clinical Immunology
Founded in 1929, The Journal of Allergy and Clinical Immunology (JACI) is the official journal of the American Academy of Allergy, Asthma, and Immunology (AAAAI).
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