Wednesday, March 18, 2015

Pioglitazone restores mitochondrial oxidant production in CGD phagocytes and enhances their bactericidal capacity

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In addition to having a nonfunctional NADPH oxidase, activated phagocytes from patients with chronic granulomatous disease (CGD) and gp91pho...
1 comment:
Tuesday, March 17, 2015

Anti-IL-23A mAb BI 655066 for treatment of moderate-to-severe psoriasis: Safety, efficacy, pharmacokinetics, and biomarker results of a single-rising-dose, randomized, double-blind, placebo-controlled trial

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Psoriasis, a chronic immune-mediated inflammatory skin disease, affects approximately 2% of the global population. Eighty to ninety percent...
2 comments:
Monday, March 9, 2015

Allergy to furry animals: New insights, diagnostic approaches, and challenges

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The prevalence of allergy to furry animals has been increasing, and allergy to cats, dogs, or both is considered a major risk factor for th...
3 comments:
Wednesday, March 4, 2015

Role of siglecs and related glycan-binding proteins in immune responses and immunoregulation

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Recent years have seen a tremendous acceleration of knowledge in the field of glycobiology, revealing many intricacies and functional contr...
1 comment:

The alpha gal story: Lessons learned from connecting the dots

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Anaphylaxis is a severe allergic reaction that can be rapidly progressing and fatal; thus, establishing the etiology of anaphylaxis is pivo...
1 comment:
Wednesday, February 11, 2015

Current biologics to treat inflammatory skin diseases

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Psoriasis and atopic dermatitis (AD) are the most common inflammatory skin conditions that share similarities, including epidermal hyperpla...
5 comments:
Tuesday, February 10, 2015

Asthma phenotypes and the use of biologic medications in asthma and allergic disease

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Asthma has traditionally been defined using non-specific clinical and physiologic variables which encompass multiple different phenotypes a...
5 comments: