Thursday, July 9, 2015

Respiratory allergy caused by house dust mites: What do we really know?

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The house dust mite (HDM) is present in human habitats around the globe, and it is a significant factor in allergic rhinitis and allergic a...
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Thursday, July 2, 2015

Anti–IL-23A mAb BI 655066 for treatment of moderate-to-severe psoriasis: Safety, efficacy, pharmacokinetics, and biomarker results of a single-rising-dose, randomized, double-blind, placebo-controlled trial

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Psoriasis is a chronic immune-mediated inflammatory skin disease with a global incidence of approximately 2%. The extent of the affected bo...
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Persistence of asthma requires multiple feedback circuits involving type 2 innate lymphoid cells and IL-33

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Little is known about the mechanisms regulating the persistence of chronic asthma. Because many allergens are perennially present, it has b...

The mechanism or mechanisms driving atopic asthma initiation: The infant respiratory microbiome moves to center stage

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It is acknowledged that key events that determine risk for the development of allergic disease frequently occur years before manifestation ...

The allergy epidemics: 1870-2010

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Allergic reactions were virtually unknown prior to 1870, and this is still the case in pre-hygiene villages in parts of the world today. Wh...
Friday, June 5, 2015

Development and validation of a novel risk score for asthma exacerbations: The risk score for exacerbations

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Asthma management involves achieving and maintaining current asthma control and preventing exacerbations. Reports have shown, however, that...
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Platelets in the immune response: Revisiting platelet-activating factor in anaphylaxis

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Platelet-activating factor (PAF) is a potent phospholipid-derived mediator thought to play a pivotal role in the etiology of numerous immun...
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