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Thursday, March 1, 2012

Preliminary evidence of bed bug allergy

An interesting Letter to the Editor in this month’s issue reports findings from a small study by Price et al (J Allergy Clin Immunol 2012;129:863-865.e2) on IgE levels in individuals that have been bitten by bed bugs. The authors developed an assay to detect specific IgE against whole bed bug (Cimex lectularius) extract as well as against a bed bug salivary protein, nitrophorin (cNP). Out of 30 subjects enrolled, greater than 50% had specific IgE to whole extract and 30% had specific IgE to both whole extract and cNP. Subjects with whole extract IgE only also had dust mite and cockroach specific IgE, which was partially cross-reactive in their assay.

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