Is there data available for the prevalence of wheat allergy in Western nations?
Although some overlap exists in the symptoms attributed to wheat allergy, specific pathophysiological reactions to wheat are currently classified into three categories: 1) IgE hypersensitivity associated wheat allergy 2) autoimmune IgA related celiac disease and 3) non celiac gluten sensitivity (NCGS). The prevalence of IgE related wheat allergy, which is most common in childhood, is estimated around 0.4-1.3%. Our review describes the prevalence of celiac disease near 1% in Western nations; however, the incidence of celiac disease has increased over time, and there is evidence of its underdiagnosis among the general population. NCGS is currently not as well understood as the other two wheat related allergies, and estimates of its prevalence are wide-ranging from 0.5-6%.