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Thursday, October 26, 2017

Can we predict fall asthma exacerbations? Validation of the seasonal asthma exacerbation index

Asthma affects about 1 in 11 American children, making it one of the most common diseases of childhood.  It carries a huge burden on families, especially during exacerbations when disease activity suddenly flares, leading to breathlessness and even death.  In this month’s issue of JACI, Hoch and colleagues discuss their research in validating the Seasonal Asthma Exacerbation Predictive Index, the saEPI (J Allergy Clin Immunol 2017; 140(4): 1130-1137).  The saEPI is a score ranging from 0 to 16 that can help predict how likely a child is to have an asthma flare.  Using data from the Preventative Omalizumab or Step-Up Therapy for Fall Exacerbations (PROSE) study, they looked at 348 children randomized to two groups: one with omalizumab, and another with guideline-based therapy alone.  They then calculated and validated the saEPI, moreover the authors looked at other factors that were associated with exacerbations.  In short, they found that children who required more aggressive treatment (high doses of inhaled corticosteroids), had higher blood eosinophils, and were younger were more likely to have a flare.  The saEPI, on the other hand, was better at determining which children were unlikely to have an asthma exacerbation.  The authors encourage providers to use data such as this to personalize their care of children at risk for asthma exacerbations. Because the children that were part of the PROSE study were largely from inner-city and minority populations and the study inclusion criteria limited some children from particpating, a similar analysis should also be performed in a more general population of children, as well as adults.  Regardless, the researchers conclude by noting the importance of such an index in managing children with asthma until even better methods are identified to classify children with asthma at risk for an asthma exacerbation.

16 comments:

  1. my health restore
    i am so happy to share this testimony with the world because generally there are so many doubts about the cure of hpv and cancer This is real take it serious, i am so happy that today i can give this testimony to the world and also help in savinglife of people who has been condemned for death just as i was ,who will believe that a herbs can cure hpv and cancer completely from thebody, i never believe that this will work, i have spend a lot of money getting drugs from the hospital to keep me healthy, it got to a time that all i was waiting for is death to come because i was broke and i already have strong outbreaks from the hpv, one day i was going through the internet asking questions online just to know more about the latest development in the medical sector to see if there is still hope then i stumbled on a post about about this great man called Dr. Ehiagwina through a publicly made a testimony on how she was also cured of ALS by this herbal doctor who is well known for his strong ancient herbal practice at first i doubted both the woman and the doctor just as so many that see's this post would doubt because medically it has been proven impossible but later i decided to give him a try so i emailed him I did not believe him that much, I just wanted to give him a try, he replied my mail and Needed some Information about me, then I sent them to him, he prepared a herbal medicine and sent it through Courier Service for delivery, he gave my details to the Courier Office. they told me that 3-5 days I will receive the package and after receiving it, i took the medicine as prescribed by him at the end of 13days that the medicine lasted, he told me to go to the hospital for a test, and i went, surprisingly after the test the doctor confirm me hpv negative and cancer disappear i thought it was a joke, i went to other hospitals and was also negative the doctors were speechless and i said it was a miracle, thank you sir for saving my life even if you cannot see this post i shall never stop testifying the impact you made in my life by restoring back my life when i was being stigmatized and even avoided by family and friends , I promise I will always testify of your good works. Dr. Ehiagwina contact: ehiagwinaherbalhome@gmail.com OR call +2348162084504 you can also add him on whatsapp.

    ReplyDelete
    Replies
    1. It's indeed a miracle I can't believe am finally free from herpes virus, am grateful to this powerful herbalist called Dr Perfect.
      I'm Chris Anderson from UK I was sick of herpes for 3 years it affected my relationship with my girlfriend when she find out I was having herpes she left me, I missed her so much because I loved her with all my heart and she always makes me happy she was the source of my happiness I wanted her to come back to me, so I took every treatment and drugs but none could cure my sickness I never lose hope because I believe I will surely get cured and be reunited with my girlfriend again so I went online to search for herpes cure and I came across a comment of a man on how this powerful herbalist cured him of herpes, I didn't hesitate I emailed him and explained my problem to him on how this herpes has affected my relationship he replied my mail and he asked for some information which I gave him and he prepared a herbal cure when he finished preparing the cure he sent it to me and instructed me on how to use it and I did it as I was instructed, five days later I couldn't find any sign of herpes that's was how I was free from herpes virus and he also did a love spell that brought back my ex girlfriend, this was the best thing that have ever happened to me am indeed grateful to Dr Perfect for the help he has rendered to me if you need help to cure your diseases or bring back your ex contact him and get your problems solved at solutiontoallproblems1@gmail.com
      You can also add him up on WhatsApp +12562513614

      He can also cure the following diseases
      1. Herpes virus
      2. Chronic venous disease
      3. Gonorrhoea
      4. Hiv/aids
      5. Alzheimers disease
      6. Asepsis
      7. Cancer
      8. Cerebrospinal meingtitis
      9. Infertility problems
      10. Als/ebv
      11. Hpv
      12. Enlargement of any type
      13. Getting back ex lover/divorce
      14. Hepatitis a,b,c
      15. Syphilis
      16. Arthritis
      17. Severe atopic dermatitis
      18. Leukaemia/lupus virus and many more....

      Delete
    2. HOW I GOT CURE TO MY HERPES WITH THE HELP OF DR EBAKO NATURAL HERBS CURE WHATSAPP HIM ON +1 (213) 861-9461


      I can’t believe this. A great testimony that i must share to all HERPES patient in the world i never believed that their could be any complete cure for HERPES or any cure for HERPES,i saw people’s testimony on sites of how DR EBAKO prepare herbal cure and brought them back to life again. i had to try it too and you can,t believe that in just few weeks i started using it all my pains stop gradually and i had to leave without the HERPES DRUGS the doctor gave to me. Right now i can tell you that few months now i have not had any pain,delay in treatment leads to death. Here is his email: doctorebakospellhome@gmail.com his WHATSAPP number is +1 (213) 861-9461
      https://drebakocurehome.blogspot.com/
      http://drebakocurehome.over-blog.com
      he can also cure you from
      HPV
      HIV
      HIV2
      Hepatitis B
      Diabetes
      etc




      ////...

      Delete
  2. Great post! I am actually getting ready to across this information, is very helpful my friend. Also great blog here with all of the valuable information you have. Keep up the good work you are doing here.
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    ReplyDelete
  3. Irrespective of receiving daily oral or future injectable depot therapies, these require health care visits for medication and monitoring of safety and response. If patients are treated early enough, before a lot of immune system damage has occurred, life expectancy is close to normal, as long as they remain on successful treatment. However, when patients stop therapy, virus rebounds to high levels in most patients, sometimes associated with severe illness because i have gone through this and even an increased risk of death. The aim of “cure”is ongoing but i still do believe my government made millions of ARV drugs instead of finding a cure. for ongoing therapy and monitoring. ARV alone cannot cure HIV as among the cells that are infected are very long-living CD4 memory cells and possibly other cells that act as long-term reservoirs. HIV can hide in these cells without being detected by the body’s immune system. Therefore even when ART completely blocks subsequent rounds of infection of cells, reservoirs that have been infected before therapy initiation persist and from these reservoirs HIV rebounds if therapy is stopped. “Cure” could either mean an eradication cure, which means to completely rid the body of reservoir virus or a functional HIV cure, where HIV may remain in reservoir cells but rebound to high levels is prevented after therapy interruption.Dr Itua Herbal Medicine makes me believes there is a hope for people suffering from,Cancer,Hiv_ Aids,Herpes,Copd,Diabetes,Hepatitis,I read about him online how he cure Tasha and Tara so i contacted him on drituaherbalcenter@gmail.com even talked on whatsapps +2348149277967 believe me it was easy i drank his herbal medicine for two weeks and i was cured just like that isn't Dr Itua a wonder man? Yes he is! I thank him so much so i will advise if you are suffering from one of those diseases Pls do contact him he's a nice man.

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  4. Dr Itua cure my HIV, I have been a ARV Consumption  for 10 years. i have been in pains until i came across Dr Itua on blogs site.I emailed him about my details of my HIV and my location i explained every thing to him and he told me that there is nothing to be scared of that he will cured me, he gave me guarantee,He ask me to pay for items fees so when i'm cured I will show gratitude I did and giving testimony of his healing herbs is what I'm going to do for the rest of you out there having HIV and other disease can see the good work of Dr Itua.I received his herbal medicine through EMS Courier service who delivered to my post office within 5 working days.Dr Itua is an honest man and I appreciate him for his good work.My GrandMa called him to appreciate him and rest of my friends did too,Is a joy to me that I'm free of taking Pills and having that fat belle is a nightmare.you will understand what i'm talking about if you have same problem I was having then not now though.I'm free and healthy Big Thanks To Dr Itua Herbal Center.I have his calendar too that he recently sent me,He Cure all kind disease Like,Cancer,Herpes,Hiv,Hepatitis B,Fibroid,Diabetes,Dercum,Copd ,and also Bring back Ex Lover Back..Here his Contact  .drituaherbalcenter@gmail.com Or Whats_app Number +2348149277967

    ReplyDelete
  5. 6 months ago I was diagnosed with COPD with 55-60% lung capacity. My doctor just said all the crying , stomping your feet will not change it so just accept it and basically patted me on the back and sent me home to die. I was devastated and was afraid to do anything. I stopped riding my bike, I was afraid to do anything that would cause any exertion. It consumed my thoughts with every breath and the fear of what to expect was almost more than I could deal with. So I couldn't get myself all time I decided to find a herbal cure online and I came acrose Doctor Itua on how he cure several people suffering from Hiv, and Herpes I gave him a call on this Number +2348149277967 also chat on whatsapp he gave me all the details about the cure i paid him for the medicine after 5 working days i receieve my herbal medicine ,I use it for two weeks that is how I get Cured and today I'm living healthy and fine I give him thanks also promise him to testify about his work,He Can also cure the following deseases..Copd,Herpes,Alzheimer's disease,Adrenocortical carcinoma.Asthma,Allergic diseases.Parkinson's Fatal Familial Insomnia Factor V Leiden Mutation ,Epilepsy Dupuytren's disease,disease,Schizophrenia,Cancer,Scoliosis,Fibromyalgia,Hiv,Hepatitis,diabetes,Coeliac disease,Creutzfeldt–Jakob disease,Cerebral Amyloid Angiopathy, Asthma.Contact...drituaherbalcenter@gmail.com..Whatsapp Number...+2348149277976

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  6. Dr Itua cure my HIV, I have been a ARV Consumption for 10 years. i have been in pains until i came across Dr Itua on blogs site.I emailed him about my details of my HIV and my location i explained every thing to him and he told me that there is nothing to be scared of that he will cured me, he gave me guarantee,He ask me to pay for items fees so when i'm cured I will show gratitude I did and giving testimony of his healing herbs is what I'm going to do for the rest of you out there having HIV and other disease can see the good work of Dr Itua.I received his herbal medicine through EMS Courier service who delivered to my post office within 5 working days.Dr Itua is an honest man and I appreciate him for his good work.My GrandMa called him to appreciate him and rest of my friends did too,Is a joy to me that I'm free of taking Pills and having that fat belle is a nightmare.you will understand what i'm talking about if you have same problem I was having then not now though.I'm free and healthy Big Thanks To Dr Itua Herbal Center.I have his calendar too that he recently sent me,He Cure all kind disease Like,Cancer,Herpes,Fibromyalgia,Hiv,Hepatitis B,Fibroid,Diabetes,Dercum,Copd ,and also Bring back Ex Lover Back..Here his Contact .drituaherbalcenter@gmail.com Or Whats_app Number +2348149277967

    ReplyDelete
  7. It's indeed a miracle I can't believe am finally free from herpes virus, am grateful to this powerful herbalist called Dr Perfect.
    I'm Chris Anderson from UK I was sick of herpes for 3 years it affected my relationship with my girlfriend when she find out I was having herpes she left me, I missed her so much because I loved her with all my heart and she always makes me happy she was the source of my happiness I wanted her to come back to me, so I took every treatment and drugs but none could cure my sickness I never lose hope because I believe I will surely get cured and be reunited with my girlfriend again so I went online to search for herpes cure and I came across a comment of a man on how this powerful herbalist cured him of herpes, I didn't hesitate I emailed him and explained my problem to him on how this herpes has affected my relationship he replied my mail and he asked for some information which I gave him and he prepared a herbal cure when he finished preparing the cure he sent it to me and instructed me on how to use it and I did it as I was instructed, five days later I couldn't find any sign of herpes that's was how I was free from herpes virus and he also did a love spell that brought back my ex girlfriend, this was the best thing that have ever happened to me am indeed grateful to Dr Perfect for the help he has rendered to me if you need help to cure your diseases or bring back your ex contact him and get your problems solved at solutiontoallproblems1@gmail.com
    You can also add him up on WhatsApp +12562513614

    He can also cure the following diseases
    1. Herpes virus
    2. Chronic venous disease
    3. Gonorrhoea
    4. Hiv/aids
    5. Alzheimers disease
    6. Asepsis
    7. Cancer
    8. Cerebrospinal meingtitis
    9. Infertility problems
    10. Als/ebv
    11. Hpv
    12. Enlargement of any type
    13. Getting back ex lover/divorce
    14. Hepatitis a,b,c
    15. Syphilis
    16. Arthritis
    17. Severe atopic dermatitis
    18. Leukaemia/lupus virus and many more....

    ReplyDelete
  8. It's indeed a miracle I can't believe am finally free from herpes virus, am grateful to this powerful herbalist called Dr Perfect.
    I'm Chris Anderson from UK I was sick of herpes for 3 years it affected my relationship with my girlfriend when she find out I was having herpes she left me, I missed her so much because I loved her with all my heart and she always makes me happy she was the source of my happiness I wanted her to come back to me, so I took every treatment and drugs but none could cure my sickness I never lose hope because I believe I will surely get cured and be reunited with my girlfriend again so I went online to search for herpes cure and I came across a comment of a man on how this powerful herbalist cured him of herpes, I didn't hesitate I emailed him and explained my problem to him on how this herpes has affected my relationship he replied my mail and he asked for some information which I gave him and he prepared a herbal cure when he finished preparing the cure he sent it to me and instructed me on how to use it and I did it as I was instructed, five days later I couldn't find any sign of herpes that's was how I was free from herpes virus and he also did a love spell that brought back my ex girlfriend, this was the best thing that have ever happened to me am indeed grateful to Dr Perfect for the help he has rendered to me if you need help to cure your diseases or bring back your ex contact him and get your problems solved at solutiontoallproblems1@gmail.com
    You can also add him up on WhatsApp +12562513614

    He can also cure the following diseases
    1. Herpes virus
    2. Chronic venous disease
    3. Gonorrhoea
    4. Hiv/aids
    5. Alzheimers disease
    6. Asepsis
    7. Cancer
    8. Cerebrospinal meingtitis
    9. Infertility problems
    10. Als/ebv
    11. Hpv
    12. Enlargement of any type
    13. Getting back ex lover/divorce
    14. Hepatitis a,b,c
    15. Syphilis
    16. Arthritis
    17. Severe atopic dermatitis
    18. Leukaemia/lupus virus and many more....

    ReplyDelete
  9. I has suffered for Human papillamvirus HPV) for 2years, I was given some tablets at the hospital but I refused to take it, They said I have to be on it for life so I don't want take a drugs everyday for life. No point in taking medicine everyday when u won't get cure from it and I was advice to seek for natural herbal cure, after some time I found DR OLIHA is the most trustful herbalist that have herbs to cure wicked symptom's,I emailed DR OLIHA for 2weeks been his patient he cured my (HPV) with his herbal. I only used his natural herbs for two weeks it was 100% cure. I'm not (HPV) patient anymore. I'm happy about it i finally got cured out of this mess been in my body for 2years. I also recommend you if you're living with (HPV) or herpes symptoms i also want you to be free contact DR OLIHA with the email attach to my post {oliha.miraclemedicine@gmail.com} you call or whats app his number on +2349038382931

    ReplyDelete
  10. Superb blog. very impressive and informative. keep posting
    skin specialist in Bangalore

    ReplyDelete
  11. It's indeed a miracle I can't believe am finally free from herpes virus, am grateful to this powerful herbalist called Dr Perfect.
    I'm Chris Anderson from UK I was sick of herpes for 3 years it affected my relationship with my girlfriend when she find out I was having herpes she left me, I missed her so much because I loved her with all my heart and she always makes me happy she was the source of my happiness I wanted her to come back to me, so I took every treatment and drugs but none could cure my sickness I never lose hope because I believe I will surely get cured and be reunited with my girlfriend again so I went online to search for herpes cure and I came across a comment of a man on how this powerful herbalist cured him of herpes, I didn't hesitate I emailed him and explained my problem to him on how this herpes has affected my relationship he replied my mail and he asked for some information which I gave him and he prepared a herbal cure when he finished preparing the cure he sent it to me and instructed me on how to use it and I did it as I was instructed, five days later I couldn't find any sign of herpes that's was how I was free from herpes virus and he also did a love spell that brought back my ex girlfriend, this was the best thing that have ever happened to me am indeed grateful to Dr Perfect for the help he has rendered to me if you need help to cure your diseases or bring back your ex contact him and get your problems solved at solutiontoallproblems1@gmail.com
    You can also add him up on WhatsApp +1 (256)-251-3614

    He can also cure the following diseases
    1. Herpes virus
    2. Chronic venous disease
    3. Gonorrhoea
    4. Hiv/aids
    5. Alzheimers disease
    6. Asepsis
    7. Cancer
    8. Cerebrospinal meingtitis
    9. Infertility problems
    10. Als/ebv
    11. Hpv
    12. Enlargement of any type
    13. Getting back ex lover/divorce
    14. Hepatitis a,b,c
    15. Syphilis
    16. Arthritis
    17. Severe atopic dermatitis
    18. Leukaemia/lupus virus and many more....

    ReplyDelete
  12. HOW I GOT CURE TO MY HERPES WITH THE HELP OF DR EBAKO NATURAL HERBS CURE WHATSAPP HIM ON +1 (213) 861-9461


    I can’t believe this. A great testimony that i must share to all HERPES patient in the world i never believed that their could be any complete cure for HERPES or any cure for HERPES,i saw people’s testimony on sites of how DR EBAKO prepare herbal cure and brought them back to life again. i had to try it too and you can,t believe that in just few weeks i started using it all my pains stop gradually and i had to leave without the HERPES DRUGS the doctor gave to me. Right now i can tell you that few months now i have not had any pain,delay in treatment leads to death. Here is his email: doctorebakospellhome@gmail.com his WHATSAPP number is +1 (213) 861-9461
    https://drebakocurehome.blogspot.com/
    http://drebakocurehome.over-blog.com
    he can also cure you from
    HPV
    HIV
    HIV2
    Hepatitis B
    Diabetes
    etc

    ReplyDelete
  13. 5 years ago I had warts, I was treated with some liquid applied to the warts they continued to grow and spread... The next 2 doctors did laser surgery to remove them. 1 year after the surgery, they grew back close to where the 1st ones were' so I was finally told it was hpv. I have had it for very long time, I contract it from my cheated boyfriend and I found out he was also infected and I end up the relationship between us. the warts was so embarrasses because it started spreading all over I have be dealing with this things for very long time the last treatment I take was About 2 years ago I applied natural treatment from Dr onokun herbal cure, a week after applying the treatment all the warts was gone. it's now 2 years and some months I don't have single wart or any symptoms of hpv. wow"" it's great, Dr onokun has finally cured me. Anyone living with hpv contact Dr onokun for natural treatment.
    His email address: dronokunherbalcure@gm‎ail.com

    ReplyDelete
  14. God bless Dr Lobo for his marvelous work in my life, I was diagnosed of HERPES since 2017 and I was taking my medications, I wasn't satisfied i needed to get the HERPES Cured out of my system, I searched about some possible cure for HERPES i saw a comment about Dr Lobo, how he cured HERPES with his herbal medicine, I contacted him and he guided me. I asked for solutions, he started the remedy for my health, he sent me the medicine through UPS SPEED POST. I took the medicine as prescribed by him and 2weeks later i was cured from HERPES, Dr Lobo truly you are so great and powerful in spiritual works, do you need his help also? Why don't you contact him through his VIA EMAIL: (Loboherbalcure@gmail.com) whatsapp him on +2349078118695

    ReplyDelete